Table 4.
Species-Specific Risk for Subsequent Infection with Causative Multidrug-resistant Gram-negative Bacteria (MDRGNB) or Infection Site Identical to Prior MDRGNB Culture during Index Hospitalization
| Subsequent MDR-GNB infection of concordant species or isolation site | |||
|---|---|---|---|
| Hazard Ratio | (95% C.I.)a | P value | |
| Initial MDRGNB species | |||
| Proteus mirabilis | 231.29 | (32.10–1666.31) | < 0.001 |
| Pseudomonas aeruginosa | 56.99 | (21.53–150.88) | < 0.001 |
| Escherichia coli | 36.83 | (17.59–77.14) | < 0.001 |
| Klebsiella pneumoniae | 15.83 | (5.17–48.48) | < 0.001 |
| Acinetobacter species | 15.25 | (7.58–30.69) | < 0.001 |
| Enterobacter species | 5.83 | (0.73–46.62) | 0.10 |
| Initial MDRGNB isolation site | |||
| Urine | 18.45 | (8.25–41.27) | < 0.001 |
| Respiratory tract | 10.52 | (6.81–16.26) | < 0.001 |
| Blood | 8.92 | (1.14–69.83) | 0.037 |
aCalculated as hazard risk between patients with positive culture for the indicated MDRGNB species or isolation site and those without any MDRGNB culture during index hospitalization