WHO recommendations |
ACIP recommendations |
Healthy elderly (> 65 yrs. of age), particularly those living in institutions |
All persons aged 65 years or more |
Patients with chronic organ failure |
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Heart, lung, liver or kidney disease, diabetes mellitus and alcoholism |
Chronic heart/lung/liver/kidney disease, DM and alcoholism |
Children > 2 yrs. old at high risk for disease (splenectomised children and sickle-cell disease) |
Patients with leukaemia/lymphoma/multiple myeloma |
Patients with immunodeficiencies particularly those with functional or anatomical asplenia |
Congenital/acquired immunodeficiencies, congenital/acquired asplenia; splenic dysfunction or splenectomy; organ transplantation or diseases requiring immunosuppressive drugs |
Prevention of subsequent pneumococcal infection in patients recovering from proven or assumed pneumococcal pneumonia |
Nephrotic syndrome |
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HIV infection |
Others including: cochlear implants, CSF leaks and cigarette smoking |