Table 5.

Impact of TRAIL-R1 expression pattern on survival of PDAC patient

Staining parameter	Total number of patients	Number of deceased patients	Median survival ± SD (95% CI) in months	p - value
Intensitiy cytoplasm
Negative to weak positive	60	48	15 ± 3.611 (7.922–22.078)
Moderate to strong positive	37	30	17 ± 3.513 (10.115–23.885)	0.735
Number of cells with positively stained cytoplasm
≤ 80%	40	37	8 ± 3.041(2.041–13.959)
> 80%	57	41	20 ± 3.855 (12.444–27.556)	0.004
Sum score cytoplasm
≤ 5	65	52	15 ± 3.733 (7.682–22.318)
> 5	32	26	17 ± 3.992 (9.177–24.823)	0.552
Staining intensity nuclei
Negative to weak positive	89	70	15 ± 1.573 (11.918–18.082)
Moderate to strong positive	8	8	13 ± 4.950 (3.298–22.702)	0.431
Number of cells with positively stained nucleus
≤ 50%	88	69	15 ± 1.430 (12.198–17.802)
> 50%	9	9	12 ± 4.472 (3.235–20.765)	0.687
Sum score nuclei
≤ 3	19	17	8 ± 1.023 (5.995–10.005)
> 3	78	61	16 ± 1.622 (12.821–19.179)	0.109

Abbreviations: SD standard deviation, CI confidence interval

P-values were estimated by log-rank-test with p ≤ 0.05 considered as significant