Table 2.
Optimal sample sizes and maximum ENBS values for WTP benchmarks
| Scenarios | Outcomes | ||||
|---|---|---|---|---|---|
| WTP value ($/QALY) | WTP benchmark | Source | Intervention duration (years) | Optimal sample size (each arm) | Maximum ENBS |
| $1014 | 1 x GDP/capita | [49] | 20 | NAa | < 0 |
| $1124 | HIV laboratory monitory strategy if two ART regimens are available | [46] | 20 | NAa | < 0 |
| $1770 | ICER of 20 year alcohol intervention | – | 20 | 500 | $11,309,000 |
| $2473 | HIV laboratory monitory strategy if three ART regimens are available (base case) | [46] | 20 | 200 | $ 67,400 |
| $3042 | 3 x GDP/capita | [49] | 20 | NAa | < 0 |
| $8000 | ICER of 10 year alcohol intervention | – | 10 | 500 | $5,108,000 |
| $31,000 | ICER of 5 year alcohol intervention | – | 5 | 240 | $2,949,000 |
aSince return on investment for a new trial was negative (ENBS < 0), conducting a new trial was not recommended for this scenario