Table 2.

Charlson Comorbidity Indexed Conditions in PAP Syndrome compared to control individuals

Indexed Comorbidity	PAP	Control	p value
Myocardial Infarction	9 (5.5%)	4 (2.4%)	0.157
Congestive Heart Failure	30 (18.3%)	5 (3%)	< 0.001
Peripheral Vascular Disease	10 (6.1%)	4 (2.4%)	0.101
Cerebrovascular Disease	15 (9.1%)	4 (2.4%)	0.009
Dementia	0 (0%)	1 (0.6%)	0.317
Chronic Pulmonary Disease	71 (43.3%)	16 (9.8%)	< 0.001
Connective Tissue Disease	14 (8.5%)	1 (0.6%)	< 0.001
Peptic Ulcer Disease	3 (1.8%)	2 (1.2%)	0.652
Mild Liver Disease	15 (9.1%)	2 (1.2%)	0.001
Diabetes without Complications	36 (22%)	20 (12.2%)	0.019
Diabetes with End-Organ Damage	8 (4.9%)	2 (1.2%)	0.054
Hemiplegia/Paraplegia	1 (0.6%)	0 (0%)	0.317
Renal Disease	16 (9.8%)	2 (1.2%)	< 0.001
Non-metastatic Cancer Hematologic Malignancy	15 (9.1%)	6 (3.7%)	0.042
Moderate/Severe Liver Disease	2 (1.2%)	0 (0%)	0.0156
Metastatic Solid Tumour	2 (1.2%)	2 (1.2%)	> 0.9999