Table 4.
Overall survival according to the CI-IR status in patients with HNSCC (locally advanced disease and recurrent or metastatic disease)
Overall survival median, (95% CI) | Log rank test | ||
Patients with locally advanced disease HNSCC treated by cetuximab potentiated chemoradiation | CI-IR, n=6 | 42.9 (5.3 to NA) months | 0.51 |
No CI-IR, n=180 | 22.6 (16.0 to 46.0) months | ||
Patients with recurrent or metastatic disease HNSCC treated by cetuximab-based systemic chemotherapy | CI-IR, n=18 | 6.5 (5.4 to NA) months | 0.17 |
No CI-IR, n=223 | 12.7 (11.1 to 16.2) months |
CI-IR, cetuximab-induced infusion reaction; HNSCC, head and neck squamous cell carcinoma.