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. 2018 Jul 23;3(5):e000346. doi: 10.1136/esmoopen-2018-000346

Table 4.

Overall survival according to the CI-IR status in patients with HNSCC (locally advanced disease and recurrent or metastatic disease)

Overall survival median, (95% CI) Log rank test
Patients with locally advanced disease HNSCC treated by cetuximab potentiated chemoradiation CI-IR, n=6 42.9 (5.3 to NA) months 0.51
No CI-IR, n=180 22.6 (16.0 to 46.0) months
Patients with recurrent or metastatic disease HNSCC treated by cetuximab-based systemic chemotherapy CI-IR, n=18 6.5 (5.4 to NA) months 0.17
No CI-IR, n=223 12.7 (11.1 to 16.2) months

CI-IR, cetuximab-induced infusion reaction; HNSCC, head and neck squamous cell carcinoma.