Figure 1.
Individual line plots for biomarkers (A) IGF-1, (B) IGF-2, (C) S100B and (D) MIA. *For patient number 2, samples were collected only for these biomarkers on predose day 12, and on day 1, there were no ‘on treatment’ samples for this patient. CR, complete response; FAS, full analysis set; MIA, melanoma-inhibitory activity; PR, partial response; UNK, unknown.