Table 2.

Median overall survival separated based on receipt of adjuvant chemotherapy. Hazard ratios showing risk of death with receipt of adjuvant chemotherapy compared to postoperative observation

	Median Overall Survival (Months)			Multivariate analysis
Group	NACRT	NACRT + AC	P	Hazard Ratio	P
Overall Cohort	36.5 (35.3 - 38.3)	35.5 (31.1 - 43.0)	0.380	0.77 (0.66 – 0.89)	<0.001
cN+/pN+	22.7 (20.9 - 24.6)	27.8 (24.2 - 32.6)	0.010	0.82 (0.67 - 1.00)	0.048
cN+/pN0	43.7 (40.5 - 50.7)	64.4 (41.9 - NR)	0.019	0.59 (0.39 - 0.88)	0.009
cN0/pN+	24.9 (21.7 - 27.3)	31.4 (24.5 - 43.5)	0.077	0.76 (0.54 - 1.06)	0.105
cN0/pN0	49.1 (43.6 - 55.4)	48.3 (35.7 - NR)	0.253	0.73 (0.41-1.30)	0.253

AC, adjuvant chemotherapy; HR, hazard ratio; NACRT, neoadjuvant chemoradiotherapy; NR, not reached.