Skip to main content
. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Aug 21;34(10):2301–2309. doi: 10.1161/ATVBAHA.114.304338

Fig. 6. Canonical Wnt signaling stimulates adhesion of monocytes to endothelial cells via p66Shc and ROS.

Fig. 6

a) Representative photographs showing Wnt3a-CM-stimulated adhesion of U937 monocytic cells to HUVEC, which is rescued by siRNA-mediated knockdown of p66Shc (n=3). b) Quantification of adherent monocytes in (a). c) Representative photographs showing effect of catalase on Wnt3a-stimulated adhesion of monocytes to HUVEC (n=3). Glycerol vehicle (Gly) was used as control. d) Quantification of adherent monocytes in (c). e) Representative photographs showing effect of NOS inhibitor L-NAME on Wnt3a-stimulated adhesion of monocytes to HUVEC (n=3). f) Quantification of adherent monocytes in (e). All the values are shown as Mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, NS=not significant. rWnt3a: recombinant Wnt3a.