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. 2018 Apr 19;73(8):2085–2088. doi: 10.1093/jac/dky153

Table 1.

Statistical summary of between-group comparisonsa of average log cfu/g of tissue

Comparison
Mean difference 95% CI Adjusted P value
group A group B
1 day post-infection
 rezafungin 20 mg/kg ip micafungin 5 mg/kg ip −0.20 −0.99 to 0.59 0.8801
 rezafungin 20 mg/kg ip amphotericin B 0.3 mg/kg ip −0.85 −1.59 to −0.10 0.0231b
 rezafungin 20 mg/kg ip vehicle ip −1.04 −1.79 to −0.30 0.0052b
4 days post-infection
 rezafungin 20 mg/kg ip micafungin 5 mg/kg ip −0.72 −1.75 to 0.32 0.2339
 rezafungin 20 mg/kg ip amphotericin B 0.3 mg/kg ip −3.30 −4.34 to −2.27 <0.0001b
 rezafungin 20 mg/kg ip vehicle ip −3.21 −4.24 to −2.17 <0.0001b
7 days post-infection
 rezafungin 20 mg/kg ip micafungin 5 mg/kg ip −0.78 −1.83 to 0.27 0.1836
 rezafungin 20 mg/kg ip amphotericin B 0.3 mg/kg ip −3.99 −5.04 to −2.94 <0.0001b
 rezafungin 20 mg/kg ip vehicle ip −3.85 −4.90 to −2.80 <0.0001b
10 days post-infection
 rezafungin 20 mg/kg ip micafungin 5 mg/kg ip −1.34 −2.41 to −0.26 0.0128b
 rezafungin 20 mg/kg ip amphotericin B 0.3 mg/kg ip −3.69 −4.76 to −2.61 <0.0001b
 rezafungin 20 mg/kg ip vehicle ip −2.89 −3.96 to −1.81 <0.0001b

ip, intraperitoneally.

a

Tukey’s multiple comparisons test.

b

Statistically significant results.