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The relative abundance (RA) of Proteobacteria in the baseline gut microbiota at acute lymphoblastic leukemia diagnosis is associated with increased cumulative incidence of first episodes of febrile neutropenia. The estimated hazard ratio was 2.12 (95% confidence interval, 1.22–3.69; P = .008) for a Proteobacteria RA of ≥0.01 vs an RA of <0.01%, adjusting for gender.
