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. 2018 Mar 15;21(8):777–785. doi: 10.1093/ijnp/pyy029

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© The Author(s) 2018. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Prior exposure to isoflurane (ISO) but not halothane (HALO) reduces the incidence of learned helplessness in Sprague-Dawley rats. (A) Procedural summary and timeline. (B) Bar graph illustrating the average (mean±SEM) number of escape failures (30 trials total) in untreated rats (n=10) and rats that had been previously anesthetized with HALO (1.5%) for 2 hours (n=12). (C) Line plot illustrating the average number of escape failures (mean±SEM) among naïve controls and HALO-treated rats in blocks of 5 trials for the duration of the test session on Day 2. (D) Bar graph illustrating the average (mean±SEM) number of escape failures in untreated rats (n=12) and rats that had been previously anesthetized with ISO (2%) for 2 hours (n=12). (E) Line plot illustrating the average number of escape failures (mean±SEM) for control and ISO-treated rats in blocks of 5 trials for the duration of the test session (Day2).