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. 2018 Apr 2;67(4):504–512. doi: 10.1093/cid/ciy145

Table 3.

Summary of Bacterial Eradication by Culture for Urogenital, Pharyngeal, and Rectal Neisseria gonorrhoeae in the Microbiologically Evaluable Population

Microbiological Response–Microbiological Outcome Gepotidacin
1500 mg
Gepotidacin
3000 mg
Total
Participants with urogenital NG at baseline 30 39 69
 Microbiological success 29 (97) 37 (95) 66 (96)
  1-sided 95% confidence interval (85.1, 100) (84.7, 100) (89.1, 100)
  1-sided P value 0.011 0.009 <0.001
  Bacterial eradication 29 (97) 37 (95) 66 (96)
 Microbiological failure 1 (3) 2 (5) 3 (4)
  Bacterial persistence 1 (3) 2 (5) 3 (4)
  Unable to determine 0 0 0
Participants with pharyngeal NG at baseline 0 2 2
 Microbiological success 0 1 (50) 1 (50)
  Bacterial eradication 0 1 (50) 1 (50)
 Microbiological failure 0 1 (50) 1 (50)
  Bacterial persistence 0 1 (50) 1 (50)
Participants with rectal NG at baseline 1 2 3
 Microbiological success 1 (100) 2 (100) 3 (100)
  Bacterial eradication 1 (100) 2 (100) 3 (100)

Data are presented as number (%) unless otherwise indicated. If either the count of successes or the count of failures was ≤5, then exact tests were conducted to compute P values.

Abbreviation: NG, Neisseria gonorrhoeae.