Table 4.
Urogenital Baseline Neisseria gonorrhoeae Antimicrobial Resistance for Selected Antimicrobials in the Microbiologically Evaluable Population
| Antimicrobial Agent | n (%) of Resistant Isolatesa | ||
|---|---|---|---|
| Gepotidacin 1500 mg |
Gepotidacin 3000 mg |
Total | |
| Number of isolates | 30 | 39 | 69 |
| Cefixime | 0 | 0 | 0 |
| Ceftriaxone | 0 | 0 | 0 |
| Ciprofloxacin | 8 (27) | 15 (38) | 23 (33) |
| Penicillin | 10 (33) | 9 (23) | 19 (28) |
| Spectinomycin | 0 | 0 | 0 |
| Tetracycline | 6 (20) | 8 (21) | 14 (20) |
Isolates were defined as resistant based on Clinical and Laboratory Standards Institute (CLSI) guidelines. For cefixime and ceftriaxone, a susceptible only breakpoint was applied. Only drugs with CLSI breakpoints were included in the summary table. The counts in this table indicate the number of isolates, not the number of participants.
aOf the 2 pharyngeal Neisseria gonorrhoeae (NG) baseline isolates, susceptibility results were only available for 1 isolate, which was resistant to ciprofloxacin, penicillin, and tetracycline. Of the 3 rectal NG baseline isolates, 2 were resistant to tetracycline.