Table 1.
Characteristic | Metabolomic Set 1 (n = 186) | Metabolomic Set 2 (n = 38) | Metabolomic Set 3 (n = 67) | Metabolomic Set 4 (n = 131) | Metabolomic Set 5 (n = 198) |
---|---|---|---|---|---|
Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | |
Age at baseline, years | 58 (53–61) | 60 (56–63) | 56 (53–62) | 57 (54–61) | 59 (55–64) |
Follow-up time, years | 20.2 (13.7–26.9) | 9.0 (5.4–14.3) | 6.2 (3.7–9.7) | 8.5 (4.6–13.5) | 8.4 (3.6–13.5) |
No. of deaths | |||||
All-cause mortality | 128 | 29 | 39 | 94 | 145 |
CVD mortality | 63 | 13 | 16 | 53 | 52 |
Cancer mortality | 34 | 9 | 10 | 20 | 34 |
BMIb, mean | 26.0 | 26.0 | 26.3 | 26.2 | 26.0 |
Smoking, cigarettes/day | 20 (15–25) | 18 (10–20) | 20 (15–25) | 20 (15–24) | 20 (13–25) |
Serum HDL cholesterol, mmol/L | 1.1 (1.0–1.3) | 1.2 (1.0–1.3) | 1.1 (1.0–1.4) | 1.2 (1.0–1.4) | 1.1 (1.0–1.3) |
Serum total cholesterol, mmol/L | 6.3 (5.6–7.1) | 6.3 (5.6–6.8) | 6.3 (5.3–7.1) | 6.4 (5.6–6.9) | 6.2 (5.4–6.8) |
History of hypertension, % | 16.1 | 10.5 | 10.5 | 21.4 | 17.7 |
History of diabetes mellitus, % | 4.3 | 2.6 | 1.5 | 3.1 | 4.0 |
Physically active, % | 24.2 | 21.1 | 23.9 | 24.4 | 19.2 |
Dietary intake per day | |||||
Total energy, kcal | 2,648 (2,231–3,063) | 2,532 (2,060–3,122) | 2,614 (2,255–3,084) | 2,601 (2,222–3,024) | 2,598 (2,070–3,066) |
Fruit, g | 121 (62–200) | 131 (72–182) | 124 (73–207) | 110 (63–185) | 98 (57–170) |
Vegetables, g | 113 (74–162) | 116 (58–158) | 106 (65–167) | 102 (73–149) | 98 (66–146) |
Red meat, g | 68.5 (52.2–95.5) | 63.1 (49.6–83.6) | 69.6 (49.5–90.7) | 68.3 (49.5–88.9) | 67.0 (49.0–88.1) |
Abbreviations: BMI, body mass index; CVD, cardiovascular disease; HDL, high-density lipoprotein; IQR, interquartile range.
a Data for continuous variables are shown as median (IQR); otherwise as indicated.
b Calculated as weight (kg)/height (m)2.