Figure 1.

The effect of the fatty acid amide hydrolase inhibitor, PF-3845 (5 mg/kg, i.p. injection), on plasma (A) corticosterone and (B) glucose levels from control and stressed rats (n=5–7/group). Plasma corticosterone and glucose concentration was determined in blood samples collected via tail-tipping from rats exposed to 0 (control), 60, 240, and 360 minutes of acute restraint stress. Data are presented as mean±SEM. ^†P<.05, ^††P<.01, and ^†††P<.001 vs vehicle-treated group at 0 (control) minute; *P<.05 and **P<.01 between vehicle- and PF-3845-treated groups at each respective time-point.