FIG. 1.

A, Schematic illustrating the diisopropylfluorophosphate (DFP) exposure paradigm and experimental design. Histopathological examinations were performed in 41 DFP-exposed and 10 saline-exposed rats at varying days post exposure (DPE). B, Scale used to score seizure severity. C, Representative traces of different patterns of seizure behavior during the first four hours following DFP intoxication. SLUD: salivation, lacrimation, urination, defecation; 2-PAM: pralidoxime (2-pyridine aldoxime methyl chloride).