Table 1.

Comparison of Registry-only Approach vs. CDM-based Approach

	Registry-only Approach	CDM-based Approach
Data Time Points	Difficulty in capturing longitudinal data points	Can capture more frequent data points from various sources
Data Elements	Data elements restricted to existing registry elements	Can capture various data elements from various data sources (e.g. EHR, claims, etc.)
Outcome Status	Dependent upon data compilation: delayed release of outcomes reports	Rapid institutional access to outcomes status report