Table 2.

PSI scores from baseline to study endpoint by experimental groups.

	Baseline	End	Changes	Effect Size	P value for mixed model
PSI total score
ATX + PT	100.3 ± 17.5, n=32	93.4 ± 19.6, n=30	−7.4 ± 15.3	.48	0.014
ATX	101.8 ± 19.6, n =32	92.8 ± 20.4, n=31	−9.0 ± 16.0	.56	0.004
PT + Placebo	96.7 ± 21.3, n =31	88.5 ± 24.3, n=31	−8.2 ± 16.9	.49	0.011
Placebo	94.7 ± 20.6, n =32	89.9 ± 21.7, n=30	−4.8 ± 11.1	.43	0.025
Overall	98.4 ± 19.8, n =127	91.2 ± 21.4 n=122	−7.4 ± 14.9	.50	<.0001
PD
ATX + PT	30.3 ± 9.5, n=32	27.6 ± 8.2, n=30	−3.3 ± 7.0	.47	0.023
ATX	31 ± 9.3, n=32	28.8 ± 9.7, n=31	−2.2 ± 6.8	.32	0.083
PT + Placebo	30.6 ± 10.3, n=31	28.2 ± 11.8, n=31	−2.4 ± 8.7	.28	0.135
Placebo	28.8 ± 9.1, n=32	26.7 ± 8.3, n=30	−2.3 ± 6.7	.34	0.077
Overall	30.2 ± 9.5, n=127	27.8 ± 9.5, n=122	−2.5 ± 7.3	.34	0.0003
PCDI
ATX + PT	29.6 ± 5.7, n=32	28.8 ± 6.2, n=30	−0.7 ± 5.2	.13	0.444
ATX	29.5 ± 6.9, n=32	27.5 ± 5.3, n=31	−1.7 ± 5.8	.29	0.085
PT + Placebo	27.8 ± 7.2, n=31	25.7 ± 7.3, n=31	−2.1 ± 4.9	.43	0.025
Placebo	27.4 ± 6.6, n=32	26.3 ± 7.0, n=30	−1.1 ± 3.8	.29	0.110
Overall	28.6 ± 6.6, n=127	27.1 ± 6.5, n=122	−1.4 ± 4.9	.29	0.002
DC
ATX + PT	40.4 ± 7.31, n=32	37.1 ± 9.5, n=30	−3.4 ± 6.2	.55	0.005
ATX	41.3 ± 7.56, n=32	36.5 ± 9.2, n=31	−5.1 ± 7.9	.65	0.001
PT + Placebo	38.3 ± 8.33, n=31	34.5 ± 8.8, n=31	−3.7 ± 6.4	.58	0.003
Placebo	38.5 ± 9.11, n=32	37 ± 9.9, n=30	−1.4 ± 4.3	.33	0.085
Overall	39.7 ± 8.11, n=127	36.3 ± 9.3, n=122	−3.4 ± 6.4	.53	<.0001

PD = Parental Distress; PCDI = Parent-Child Dysfunctional Interaction; DC = Difficult Child.