Table 5. Sensitivity and specificity of LTBI by latent class analysis method.
Test | Sensitivity (95% CI) | Specificity (95% CI) |
---|---|---|
TST (T)* | 76% | 77% |
(56%–97%) | (57%–98%) | |
QFT-GIT (Q) | 69% | 69% |
(55%–83%) | (48%–91%) | |
Exposure (E) | 72% | 38% |
(67%–76%) | (32%–44%) |
Estimated Prevalence of LTBI = 60% (95%CI: 42%–78%). Probability of being LTBI Positive: T+Q+E+ (94%), T+Q+E- (90%), T+Q-E+ (74%), T+Q-E- (65%), T-Q+E+ (56%), T-Q+E- (45%), T-Q-E+ (20%) and T-Q-E- (14%).
*TST induration cut-off used is >5mm as the cut-off. (Analysis using TST cut-off>10mm is given as S6 Table)