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. 2018 Aug 1;13(8):e0200677. doi: 10.1371/journal.pone.0200677

Table 4. Discography studies–pooled results.

MCs type(s) Study OR (95% CI)
MCs, any type Braithwaite 1998 [52] 9.13 (2.06–40.56)
Ito 1998 [53] 5.14 (1.25–21.09)
Weishaupt 2001 [54] 19.93 (5.50–72.31)
Kokkonen 2002 [55] 1.19 (0.52–2.73)
Lim 2005 [56] 0.46 (0.12–1.77)
O'Neill 2008 [57] 8.69 (3.03–24.96)
Kang 2009 [58] 1.09 (0.4–2.95)
Chen 2011 [60] 14.91 (6.41–34.67)
TOTAL (Random) 4.01 (1.52–10.61)
MCs1 Braithwaite 1998 [52] 9.58 (0.52–176.75)£
Weishaupt 2001 [54] 13.59 (2.92–63.28)*
Kokkonen 2002 [55] 1.34 (0.48–4.00)
O'Neill 2008 [57] 7.90 (1.79–34.97)
Thompson 2009 [59] 9.32 (6.17–14.09)*
TOTAL (Random) 6.14 (2.47–15.27)
MCs2 Braithwaite 1998 [52] 6.96 (1.54–31.50)
Weishaupt 2001 [54] 15.46 (1.89–126.67)**
Kokkonen 2002 [55] 1.03 (0.36–2.95)
O'Neill 2008 [57] 9.48 (2.17–41.37)
Thompson 2009 [59] 0.90 (0.62–1.31)**
TOTAL (Random) 3.15 (1.00–9.93)

The association between Modic changes and LBP for studies using concordant pain on provocative discography as outcome.¨

*: MCs1 vs. non-MCs1

**: MCs2 vs. non-MCs2

£: Added 0.5 to all cells in 2x2 table.