Table 4. Discography studies–pooled results.
MCs type(s) | Study | OR (95% CI) |
---|---|---|
MCs, any type | Braithwaite 1998 [52] | 9.13 (2.06–40.56) |
Ito 1998 [53] | 5.14 (1.25–21.09) | |
Weishaupt 2001 [54] | 19.93 (5.50–72.31) | |
Kokkonen 2002 [55] | 1.19 (0.52–2.73) | |
Lim 2005 [56] | 0.46 (0.12–1.77) | |
O'Neill 2008 [57] | 8.69 (3.03–24.96) | |
Kang 2009 [58] | 1.09 (0.4–2.95) | |
Chen 2011 [60] | 14.91 (6.41–34.67) | |
TOTAL (Random) | 4.01 (1.52–10.61) | |
MCs1 | Braithwaite 1998 [52] | 9.58 (0.52–176.75)£ |
Weishaupt 2001 [54] | 13.59 (2.92–63.28)* | |
Kokkonen 2002 [55] | 1.34 (0.48–4.00) | |
O'Neill 2008 [57] | 7.90 (1.79–34.97) | |
Thompson 2009 [59] | 9.32 (6.17–14.09)* | |
TOTAL (Random) | 6.14 (2.47–15.27) | |
MCs2 | Braithwaite 1998 [52] | 6.96 (1.54–31.50) |
Weishaupt 2001 [54] | 15.46 (1.89–126.67)** | |
Kokkonen 2002 [55] | 1.03 (0.36–2.95) | |
O'Neill 2008 [57] | 9.48 (2.17–41.37) | |
Thompson 2009 [59] | 0.90 (0.62–1.31)** | |
TOTAL (Random) | 3.15 (1.00–9.93) |
The association between Modic changes and LBP for studies using concordant pain on provocative discography as outcome.¨
*: MCs1 vs. non-MCs1
**: MCs2 vs. non-MCs2
£: Added 0.5 to all cells in 2x2 table.