Fig 5. Bone volume data for studies looking at interventions of human proteins and hormones, cells and tissues, minerals, elements and chemicals, pharmaceuticals or animal derivatives.

Forest plot illustrating mean difference in cubic millimetre (mm³) of bone volume as measured by different histological or radiological measures. *Since none of the control groups healed, the increase in bone volume was set as 0 and the standard deviation as 0.0000001 in order to be able to illustrate those results in a forest plot using STATA. Abbreviations: BMP2, bone morphogenetic protein 2; BMSCs, bone marrow stromal cells; CI, confidence interval; HA, hyaluronic acid; IGF-1, insulin growth factor-1; MSCs, mesenchymal stem cells; OPG, osteoprotegerin; PI, proteasome inhibitor; SDF-1, stromal cell derived factor 1; VEGF, vascular endothelial growth factor; wks, weeks; WMD, weighted mean difference.