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. 2018 Aug 1;13(8):e0201077. doi: 10.1371/journal.pone.0201077

Table 2. Number of evaluations under investigation by category*.

Group Number of evaluations included in tables Number of evaluations included in forest plots Total
Animal derivatives 27 5 32
Plant extracts 23 13 36
Minerals / elements / chemicals 25 7 32
Pharmaceuticals 16 13 29
Cells / tissues 32 18 50
Vibration / motion 2 5 7
Light / lasers 3 0 3
Gases 3 5 8
Human proteins / hormones 59 41 100
Total 190 107 297

*Combination therapies are duplicated in all groups they pertain to, e.g. mesenchymal stem cells + vascular endothelial growth factor will be counted in “cells / tissues” and “human proteins / hormones”.

Single therapies tested in multiple concentrations are counted more than once, e.g. Ngueguim 2012 evaluates two plant based therapies: both therapies are evaluated at three different concentrations, thereby contributing 6 evaluations.

A total of 197 studies were included, investigating a total of 204 distinct therapies.

Total number of studies included in tables = 136, total number of studies included in forest plots = 61.