Table 2. Linkage disequilibrium analysis between the p.Arg261* variant in Karachays and microsatellites close to the PAH gene.
Marker | Allele | θ, сМ | χ2 | δ± 95%Cl | g | g (mean) |
---|---|---|---|---|---|---|
D12S1588 | 5 | 4.82 | 30.2 | 0.58±0.16 | 11.08 | 10.2±2.7 |
D12S1727 | 8 | 2.81 | 34.1 | 0.71±0.15 | 12.24 | |
РАН | p.Arg261* | |||||
D12S78 | 8 | 1.87 | 93.0 | 0.92±0.08 | ||
D12S338 | 1 | 1.87 | 64.5 | 0.93±0.08 | ||
D12S317 | 16 | 4.28 | 66.4 | 0.73±0.12 | 7.17 |