Figure 3. Spectrum of high-impact somatic mutations and their sample-wise distribution. High-impact somatic mutations of low-density lipoprotein receptor-related protein 1 (LRP1B) and SMAD family member 4 (SMAD4) were mutated in the highest proportion of samples (3/9 samples). We were unable to detect any actionable mutation in S6. Right color bar panel represents actionability or druggability status of these genes. Numbers of mutations in a gene of a tumor are presented according to the color key. The bar plot in the top panel presents the total number of high-impact somatic mutations detected.
