Table 3. ESD performance, histopathology and management.
| Biopsy | Pre-ESD diagnosis | Resection | Lateral margin | Deep Margin | Invasion depth | Lympho- vascular invasion | Further management (months) | Result |
| LGD | Adenoma | En-bloc | R0 | R1 | SM3 | Yes | Surgery | No residual cancer in resected specimen |
| LGD | Adenoma | Aborted 1 | – | – | – | No | Emergency resection | T3N0 tumor in resected specimen |
| HGD | Adenoma | En-bloc 1 | R0 | R0 | Sm1 | Yes | Endoscopy (18) | No recurrence or residue |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (28) | No recurrence or residue |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (6) | No recurrence or residue |
| HGD | Adenoma | En-bloc | R0 | R0 | Sm2 | Yes | Endoscopy (19) | No recurrence or residue |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm1 | No | No follow-up 2 | – |
| LGD | Adenoma | Piecemeal 1 | R0 | R0 | Sm1 | No | Endoscopy (10) | No recurrence or residue |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm1 | Yes | Endoscopy (12) | No recurrence or residue |
| LGD | Adenoma | En-bloc | R0 | R1 | Sm3 | No | Surgery | No residual cancer in resected specimen |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm3 | No | Surgery | No residual cancer in resected specimen |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm3 | No | Endoscopy (6) 3 | No recurrence or residue |
| HGD | Adenoma | En-bloc | R0 | R0 | Sm3 | No | Surgery | No recurrence or residue |
| – | Adenoma | En-bloc | R0 | R0 | Sm1 | No | Awaits endoscopy | No recurrence or residue |
| – | Adenoma | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (4) | No recurrence or residue |
| LGD | Adenoma | En-bloc | R0 | R0 | Sm2 | No | MRI + endoscopy (3) | No recurrence or residue |
| LGD | Suspected Ca | Piecemeal | R0 | R0 | Sm1 | No | No follow-up 2 | – |
| LGD | Suspected Ca | Piecemeal | RX | R0 | Sm1 | No | Endoscopy (20) | No recurrence or residue |
| LGD | Suspected Ca | Piecemeal | RX | RX | Sm2 | Yes | MRI + Endoscopy (24) | No recurrence or residue |
| HGD | Suspected Ca | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (21) | No recurrence or residue |
| LGD | Suspected Ca | En-bloc | R0 | R0 | Sm2 | No | Surgery | No residual cancer in resected specimen |
| Ca | Confirmed Ca | En-bloc 1 | R0 | RX | Sm2 | No | Surgery | Residual cancer in resected specimen |
| HGD | Suspected Ca | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (15) | Recurrence, Radiation therapy or surgery |
| Ca | Confirmed Ca | En-bloc | R0 | R1 | Sm3 | No | Endoscopy (2) | No recurrence or residue |
| HGD | Suspected Ca | En-bloc | R0 | R0 | Sm2 | Yes | MRI + Endoscopy (7) 3 | No recurrence or residue |
| HGD | Suspected Ca | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (8) | No recurrence or residue |
| HGD | Suspected Ca | En-bloc | R0 | R0 | Sm1 | No | Endoscopy (6) | No recurrence or residue |
| Ca | Confirmed Ca | En-bloc | R0 | R1 | Sm3 | No | Endoscopy (3) | No recurrence or residue |
| LGD | Suspected Ca | En-bloc | R0 | R1 | Sm2 | No | Endoscopy (14) | No recurrence or residue |
LGD, low-grade dysplasia; HGD, high-grade dysplasia; Ca, cancer; MRI, magnetic resonance imaging; MDT, multidisciplinary team
1
Perforation during ESD
2
Due to spread of non-colorectal cancer
3
Patient refused surgery despite MDT recommendation.