Table 5.
The concentrations of soluble adhesion molecules in patients with preterm labor and intact membranes, preterm PROM and acute pyelonephritis compared to normal pregnancy
| Normal Pregnancy (n=100) |
Preterm Labor with Intact Membranes (n=53) |
P value | Preterm PROM (n=24) |
P value | Acute pyelonephritis (n=25) |
P value | |
|---|---|---|---|---|---|---|---|
| Soluble E-selectin (ng/mL) | 45.1 (33.9–53.3) |
44.8 (34.6–57.8) |
0.46 | 39.2 (28.7–70.5) |
0.98 | 99.1 (78.6–175.2) |
<0.001 |
| Soluble L-selectin (ng/mL) | 669.7 (583.4–830.4) |
605.7 (542.4–761.2) |
0.13 | 518.1 (429.1–638.7) |
<0.001 | 587.2 (500.2–750.9) |
0.06 |
| Soluble P-selectin (ng/mL) | 92.6 (72.4–111.1) |
102.5 (83.2–133.3) |
0.02 | 94.2 (75.1–122.5) |
0.74 | 83 (59.7–101.3) |
0.16 |
| Soluble VCAM-1 (ng/mL) | 507.8 (451.8–593.7) |
454 (402.6–529.7) |
0.005 | 445.3 (376.2–472.6) |
<0.001 | 671.3 (543.7–713.4) |
<0.001 |
| Soluble ICAM-1 (ng/mL) | 266.7 (217.6–312.8) |
245.2 (161.6–288.2) |
0.05 | 234.3 (167.6–329.5) |
0.2 | 442.8 (332.6–622.2) |
<0.001 |
| Soluble PECAM-1 (ng/mL) | 6.7* (5.1–8.4) |
not measured | - | not measured | - | 5.8*** (4.3–7.2) |
0.12 |
NOTE: P value (obstetrical condition vs. normal pregnancy); ICAM-1: intercellular adhesion molecule; PECAM-1: platelet endothelial cell adhesion molecule; PROM: prelabor rupture of membranes; VCAM-1: vascular cell adhesion molecule;
*
data not available in 3 cases;
***
data not available in 4 cases.
Data is presented as median (interquartile range)