Table 2.
Measurement of expression of a subset of biomarkers by qPCR over time during the transmission stage of the parasite within the mosquito.
| Gene | PlasmoDB ID | Day 0 | 6 hours | Day 1 | Day 2 | Day 4 | Day 6 | Day 8 |
|---|---|---|---|---|---|---|---|---|
| Conserved | PF3D7_0931300 | 5 | 8.9 | 36 | NA | 240 | 18,500 | 1,690,000 |
| CSP | PF3D7_0304600 | 0 | 51.5 | 65.8 | 416 | 1740 | 66,800 | 1,620,000 |
| DHFS-FPGS | PF3D7_1324800 | 37.9 | 58.7 | 55 | 13,700 | 6970 | 62,800 | 192,000 |
| ALBA1 | PF3D7_0814200 | 0 | 4 | 0 | 341 | 1660 | 13,700 | 44,400 |
| GAPDH | PF3D7_1462800 | 0 | 111 | 716 | 6020 | 84,800 | 1,030,000 | 3,250,000 |
| H2B | PF3D7_1105100 | 0 | 2430 | 26,200 | 105,000 | 276,000 | 1,420,000 | 4,620,000 |
| P23 | PF3D7_1453700 | 0 | 70 | 592 | 10,100 | 61,500 | 500,000 | 1,080,000 |
| RACK | PF3D7_0826700 | 0 | 35 | 314 | 4840 | 66,500 | 386,000 | 989,000 |
| TRP1 | PF3D7_1438900 | 0 | 111 | 915 | 5250 | 48,100 | 445,000 | 1,710,000 |
| WARP | PF3D7_0801300 | 0 | 312 | 300 | 204,000 | 14,000 | 6390 | 11,900 |
Values shown represent mRNA copy number per 100 ng template RNA.