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. 2018 Aug 1;9(8):822. doi: 10.1038/s41419-018-0870-9

Fig. 6. NS1619 and DHEA sensitize T-ALL cells to TRAIL.

Fig. 6

A Specific cell death upon 24 h of treatment with NS1619, DHEA or NS1619 + DHEA in the absence ( − ) or presence ( + ) of TRAIL in TALL-1 cells (three independent experiments, three replicates each), PDX (N = 4, three replicates each), primary T-ALL samples (N = 7, three replicates each), and primary thymocytes (N = 4, three replicates each). Mean values and SE bars are shown. B Quantitative RT-PCR analysis of TRAIL-R2 mRNA expression in normal thymocytes (N = 3), TALL-1 cells (8 repeats), primary T-ALL samples (N = 7), and PDX (N = 5). β2-microglobulin (B2M) was used as a housekeeping mRNA and values were scaled against those obtained for thymocytes. Mean values and SE bars are shown