Figure 3.
Bacterial colonization in the murine acute pneumonia model. Each mouse was infected by 2 × 107 CFU of the indicated strain intranasally. 12 h after infection, mice were sacrificed and bacterial loads in the lungs were determined. Bacterial loads in mice infected with wild-type PA14 and the oprH:Tn, foxA:Tn, hasR:Tn, and fpvA:Tn. Bars represent medians, and error bars represent SEM. *p < 0.05; **p < 0.01 compared to wild-type PA14 by the Kruskal–Wallis with Dunn’s multiple comparison test. NS, not significant.