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MK-8931 (20 mg/kg) treatment significantly reduced Aβ 40 levels in the murine cortex (t(6) = 9.5, p < 0.0001, two-tailed unpaired Student’s t-test). Brain samples were taken 4 h after acute treatment and were analyzed by Sandwich-ELISA assay. Data presented as mean ± SEM, n = 4.
