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Colonization with non-toxigenic Clostridium difficile M3 and challenge with toxigenic strain J9 during daily oral ampicillin administration for 5 days. Both J9 and M3 are susceptible to ampicillin. Animals are indicated by ovals: open ovals indicate no detection of C. difficile in stool; gray-shaded ovals indicate detection of non-toxigenic M3 in stool. PO, orally. From Merrigan et al. (2009).
