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. 2018 Jul 26;9:798. doi: 10.3389/fphar.2018.00798

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Copyright © 2018 Ramírez, Conejo-García, Griñán-Lisón, López-Cara, Jiménez, Campos, Marchal and Boulaiz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Determination of the effects of the combination of gef gene expression with bozepinib, FC-26c, FC-29b, and FC-30b2 on cell proliferation. (A) MCF-7 and MCF-7TG cell lines were treated with IC₅₀ and 2^∗IC₅₀ of different compounds during 15 days. Data are expressed as the mean ± standard error of the mean of three independent experiments. (B) Percentage of cell viability after 15 days of treatment with different compounds expressed in comparison to the maximal MCF-7 (100%). The statistical analysis was performed using each cell line without drug exposure as controls. ^∗P < 0.05, ^∗∗P < 0.01 (t-test).