FIGURE 6.

Combination of gef gene expression and drugs induce cell cycle arrest in G0/G1. MCF-7 and MCF-7TG cells were mock-treated (control) or treated with IC₅₀ of bozepinib, FC-26c, FC-29b, and FC-30b2 for 72 h. Then, cells were trypsinized and analyzed by FACScan to distinguish populations of cells in different phases of the cycle as described in the section “Materials and Methods.” (A) Representative images from flow cytometry analysis. (B) Data are expressed as the mean ± standard error of the mean of three independent experiments. ^∗P < 0.05, ^∗∗P < 0.01 (t-test).