miRNA Profiling of MB and Normal Cerebellar Tissues
(A) Upregulated miRNA scripts. (B) Downregulated miRNA scripts (>20-fold change). In both cases, relative fold change with respect to normal cerebellar tissues was used to calculate the final fold change. The housekeeping genes SNORD61, SNORD68, SNORD72, SNORD95, SNORD96A, and RNU6B/RNU6-2 were used as internal controls. Expression of miR-217 in different MB cell lines by real-time qPCR compared to (C) neuronal progenitor cells (NPC) and (D) SVG p12. Data are shown as the mean ± SD of three separate experiments (Student’s t test; *p < 0.05; n = 3).