Table 3.

Intra-patient and inter-patient variance as standard deviation after adjusting for time and brain region effects. The intra-class correlation coefficient (ICC) was determined as the correlation of two measurements of the same patient and the same measurement region after correcting for time effects. Note the smallest ICC in NAWM measures representing the highest variability in individual patient NAWM relative to group variability.

Measure	Region	Intra-subject variance as σwithin	Inter-subject variance as σbetw	Total variance as σtotal	ICC
MWF	NAWM	0.005	0.004	0.007	0.340
	DAWM	0.009	0.021	0.023	0.860
	T2L	0.010	0.020	0.022	0.793
DVF	NAWM	0.527	0.472	0.707	0.446
	DAWM	4.114	8.987	9.884	0.827
	T2L	3.934	16.278	16.746	0.945