Figure 4. MEK162 has a lower cytotoxicity than omipalisib. (A) Graphs (mean±S.E.M.) showing percentage of cytotoxicity in C76N (left), PD1N (middle) and C42N (right) cells calculated as a function of LDH activity according to manufacturer’s instructions. (B) Pictures showing C76N cells treated with vehicle or omipalisib at the indicated concentrations. Cells rounded up and detached from the surface. Less cells are seen attached at the higher dose. Scale bar represents 100 μm.