FIG 4 .

Host-dependent C. trachomatis and C. pneumoniae peptide antigens specifically reactive with human C. trachomatis-positive sera but not with immune mouse sera. A library of 271 C. trachomatis and 153 C. pneumoniae peptide antigens was screened with the C. trachomatis-positive and -negative human serum pools. These peptides had previously been nonreactive in screens performed with hyperimmune monospecies-specific anti-C. trachomatis and anti-C. pneumoniae mouse sera (39). A total of 100 peptides showed reactivity above background, and the top-ranked 38 C. trachomatis and 8 C. pneumoniae peptide antigens derived from immunodominant proteins are shown. Signal intensities are shown in Log₂ RLU bars as described for Fig. 2.