FIG 6 .

IgG1 and IgG3 antibodies against C. trachomatis and C. pneumoniae peptides in 48 individual sera. Sera from 48 C. trachomatis-positive women that covered the spectrum of C. trachomatis and C. pneumoniae MIF titers (rows 2 and 3), as well as the racial origin of the study subject, were selected. A total of 56 unique C. trachomatis and C. pneumoniae peptide antigens with potential utility for human population surveys were tested with these individual sera. These peptides are divided into 6 sets based on C. trachomatis and C. pneumoniae species, serovar specificity, source proteins, reaction frequency, and the immunoglobulin subclasses detected. The host-independent peptides shown in black font had previously reacted with mouse anti-C. trachomatis sera (39), while the host-dependent peptides shown in red font were not recognized by mouse sera but showed reactivity in this study with human sera. Blue font indicates eight non-serovar D peptides from OmpA variable domains 1 and 2. The column following the peptide designations shows C. trachomatis or C. pneumoniae specificity. Individual sera are numerically identified in the top row and are arranged in order of their average level of IgG1 reactivity with the first set of 11 C. trachomatis peptides. Peptide reactivities with the individual 48 sera are indicated by color intensities (legend at bottom), and absence of reactivity is shown by white cells.