siNFκB MDA-MB-231
Fold Change	Gene Symbol	Description	GO Biological Process	GO Molecular Function
25.9	ALDH1A3	aldehyde dehydrogenase 1 family, member A3	retinoic acid biosynthetic process, metabolic process	aldehyde dehydrogenase (NAD) activity; oxidoreductase activity
21.19	AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	retinoid metabolic process; cellular aldehyde metabolic process; steroid metabolic process; oxidation-reduction process	aldo-keto reductase (NADP) activity; oxidoreductase activity
11.78	TP63	tumor protein p63	replicative cell aging	DNA binding transcription factor activity
10.72	DHRS9	dehydrogenase/reductase (SDR family) member 9	androgen metabolic process; progesterone metabolic process; retinol metabolic process	alcohol dehydrogenase (NAD) activity; oxidoreductase activity; oxidoreductase activity
9.4	PTGES	prostaglandin E synthase	prostaglandin metabolic process; cyclooxygenase pathway; response to lipopolysaccharide; fatty acid metabolic process	glutathione binding; isomerase activity
8.23	DHRS3	dehydrogenase/reductase (SDR family) member 3	retinol metabolic process; oxidation-reduction process; metabolic process	nucleotide binding; dehydrogenase activity; electron carrier activity; oxidoreductase activity
7.02	RDH10	retinol dehydrogenase 10 (all-trans)	retinoid metabolic process	oxidoreductase activity
5.01	GPX2	glutathione peroxidase 2 (gastrointestinal)	oxidation-reduction process; response to oxidative stress; cellular oxidant detoxification	electron carrier activity; peroxidase activity; oxidoreductase activity
5.01	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		peroxidase activity; lipid binding; enzyme binding; heme binding; metal ion binding; oxidoreductase activity
4.57	PTGFRN	prostaglandin F2 receptor inhibitor	lipid particle organization	protein binding
3.5	AKR1C2	aldo-keto reductase family 1, member C2; aldo-keto reductase family 1 member C2-like	lipid metabolic process; prostaglandin metabolic process; steroid metabolic process	oxidoreductase activity; carboxylic acid binding
3.48	STS	steroid sulfatase (microsomal), isozyme S	steroid metabolic process	steryl-sulfatase activity; sulfuric ester hydrolase activity; metal ion binding; catalytic activity; hydrolase activity
3.42	GSTT1	glutathione S-transferase theta 1	glutathione metabolic process; xenobiotic metabolic process; oxidation-reduction process	glutathione transferase activity; glutathione peroxidase activity; protein binding
3.13	MAOA	monoamine oxidase A	xenobiotic metabolic process; oxidation-reduction process	primary amine oxidase activity; oxidoreductase activity
3.05	CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	cellular aromatic compound metabolic process; exogenous drug catabolic process; oxidation-reduction process	iron ion binding; oxidoreductase activity
2.92	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	phospholipid metabolic process; protein phosphorylation; inflammatory response	lipid kinase activity; ATP binding
278	CP	ceruloplasmin (ferroxidase)	copper ion transport; oxidation-reduction process;	ferroxidase activity; copper ion binding; chaperone binding; oxidoreductase activity; metal ion binding
2.62	SQRDL	sulfide quinone reductase-like (yeast)	sulfur amino acid metabolic process; cellular nitrogen compound metabolic process; oxidation-reduction process	sulfide:quinone oxidoreductase activity; oxidoreductase activity
2.52	CYB5A	cytochrome b5 type A (microsomal)	L-ascorbic acid metabolic process; response to cadmium ion; oxidation-reduction process	aldo-keto reductase (NADP) activity; enzyme binding; heme binding; metal ion binding
2.39	SEPW1	selenoprotein W, 1	cell redox homeostasis	antioxidant activity; selenium binding
2.38	IDO1	indoleamine 2,3-dioxygenase 1	immune system process; chronic inflammatory response	electron carrier activity; heme binding; metal ion binding; oxidoreductase activity
2.36	NDUFB9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22 kDa	mitochondrial electron transport, NADH to ubiquinone; respiratory electron transport chain; oxidation-reduction process	protein binding; NADH dehydrogenase activity
2.35	SRD5A3	steroid 5 alpha-reductase 3	androgen biosynthetic process; oxidation-reduction process; protein glycosylation; lipid metabolic process	oxidoreductase activity
2.21	BLVRB	biliverdin reductase B (flavin reductase (NADPH))	heme catabolic process; oxidation-reduction process	riboflavin reductase (NADPH) activity; oxidoreductase activity
2.18	NDUFS6	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13 kDa (NADH-coenzyme Q reductase)	mitochondrial electron transport, fatty acid metabolic process; oxidation-reduction process	NADH dehydrogenase activity; electron carrier activity
2.16	PTGER4	prostaglandin E receptor 4 (subtype EP4)	immune response; adenylate cyclase-modulating G-protein coupled receptor signaling pathway	prostaglandin E receptor activity; protein binding; signal transducer activity; prostaglandin receptor activity
2.13	IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	glyoxylate cycle; tricarboxylic acid cycle; isocitrate metabolic process; 2-oxoglutarate metabolic process	magnesium ion binding; isocitrate dehydrogenase activity; oxidoreductase activity
2.13	UQCRB	ubiquinol-cytochrome c reductase binding protein	oxidative phosphorylation; mitochondrial electron transport, oxidation-reduction process	protein binding
2.06	BCKDHA	branched chain keto acid dehydrogenase E1, alpha polypeptide	branched-chain amino acid catabolic process; oxidation-reduction process;	alpha-ketoacid dehydrogenase activity; carboxy-lyase activity; metal ion binding; oxidoreductase activity
2.06	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	fatty acid metabolic process; prostaglandin metabolic process	NAD binding; oxidoreductase activity;
2.06	PIP4K2C	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma	phosphatidylinositol phosphorylation	ATP binding; nucleotide binding; kinase activity; transferase activity
2.05	GCLC	glutamate-cysteine ligase, catalytic subunit	response to oxidative stress; glutamate metabolic process; glutathione metabolic process	coenzyme binding; magnesium ion binding; glutamate-cysteine ligase activity; ATP binding
2.05	TSTD1	thiosulfate sulfur transferase (rhodanese)-like domain containing 1; F11 receptor	sulfide oxidation	protein binding; transferase activity
2.04	XDH	xanthine dehydrogenase	xanthine catabolic process; oxidation-reduction process; regulation of reactive oxygen species	iron ion binding; electron carrier activity; oxidoreductase activity, metal ion binding
2.02	DHODH	dihydroorotate dehydrogenase (quinone)	nucleotide biosynthetic process; response to organic cyclic compound	dehydrogenase activity; oxidoreductase activity
2.01	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	phospholipid transport	protein binding; lipid binding; phosphatidylinositol transporter activity
1.99	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1	xenobiotic metabolic process; oxidation-reduction process	iron ion binding; oxidoreductase activity; steroid hydroxylase activity
1.98	RAD51	RAD51 recombinase	DNA repair; DNA recombinase assembly	DNA binding; recombinase activity
1.75	GSTK1	glutathione S-transferase kappa 1	glutathione metabolic process; xenobiotic metabolic process; oxidation-reduction process	transferase activity; peroxidase activity; receptor binding; oxidoreductase activity
1.72	HEBP2	heme binding protein 2	mitochondrial membrane potential; mitochondrial membrane permeability; response to reactive oxygen species	protein binding
1.64	POR	P450 (cytochrome) oxidoreductase	xenobiotic metabolic process; response to nutrient	enzyme binding; hydrolase activity; electron transfer activity
1.63	CYP4Z1	cytochrome P450, family 4, subfamily Z, polypeptide 1	oxidation-reduction process	iron ion binding; heme binding; aromatase activity; oxidoreductase activity; metal ion binding
1.52	PEX11A	peroxisomal biogenesis factor 11 alpha	peroxisome organization; lipid metabolic process	protein binding; protein homodimerization activity
1.51	COX6C	cytochrome c oxidase subunit VIc	mitochondrial electron transport; hydrogen ion transmembrane transport	oxidase activity
−1.52	NOXA1	NADPH oxidase activator 1	superoxide metabolic process; regulation of hydrogen peroxide metabolic process	NADPH oxidase activity; enzyme binding
−1.55	NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	nitric oxide biosynthetic process; apoptotic process	nitric-oxide synthase binding
−1.6	CYP2U1	cytochrome P450, family 2, subfamily U, polypeptide 1	xenobiotic metabolic process; arachidonic acid metabolic process; oxidation-reduction process	iron ion binding; oxidoreductase activity
−1.65	GPX3	glutathione peroxidase 3 (plasma)	response to lipid hydroperoxide; oxidation-reduction process; response to oxidative stress	glutathione peroxidase activity; transcription factor binding; selenium binding; oxidoreductase activity
−1.67	GSTP1	glutathione S-transferase pi 1	response to reactive oxygen species; glutathione metabolic process; xenobiotic metabolic process	glutathione transferase activity; nitric oxide binding; transferase activity
−1.67	MT1A	metallothionein 1A	cellular response to cadmium ion; cellular response to zinc ion	protein binding; metal ion binding
−1.73	GSTT2	glutathione S-transferase theta 2; glutathione S-transferase theta 2B (gene/pseudogene)	glutathione metabolic process; xenobiotic metabolic process;	glutathione transferase activity; transferase activity; protein binding
−1.74	MSRB3	methionine sulfoxide reductase B3	response to oxidative stress; protein repair; oxidation-reduction process	zinc ion binding; oxidoreductase activity
−1.76	ARG2	arginase 2	urea cycle; arginine metabolic process; nitric oxide biosynthetic process	arginase activity; metal ion binding; hydrolase activity
−2.56	GSTM1	glutathione S-transferase mu 1	glutathione metabolic process; xenobiotic metabolic process	glutathione transferase activity; enzyme binding