1.78 |
HSD17B2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
steroid biosynthetic process; oxidation-reduction process |
estradiol 17-beta-dehydrogenase activity; testosterone dehydrogenase activity |
1.7 |
COX11P1 |
COX11 cytochrome c oxidase assembly homolog (yeast) pseudogene 1 |
mitochondrial electron transport, hydrogen ion transmembrane transport |
cytochrome-c oxidase activity |
1.64 |
BRCA1 |
breast cancer 1, early onset |
DNA repair, double-strand break repair via homologous recombination |
DNA binding, ligase activity |
1.58 |
FAR1 |
fatty acyl CoA reductase 1 |
glycerophospholipid biosynthetic process; oxidation-reduction process |
fatty-acyl-CoA reductase (alcohol-forming) activity; oxidoreductase activity |
1.58 |
RB1 |
retinoblastoma 1 |
cell cycle checkpoint, G1/S transition of mitotic cell cycle |
DNA binding transcription factor activity, enzyme binding |
1.57 |
NUDT4 |
nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
cyclic nucleotide metabolic process, inositol phosphate metabolic process |
hydrolase activity, endopolyphosphatase activity, protein binding |
1.56 |
HPGD |
hydroxyprostaglandin dehydrogenase 15-(NAD) |
fatty acid metabolic process, prostaglandin metabolic process |
NAD binding, prostaglandin E receptor activity, oxidoreductase activity |
1.54 |
PEX1 |
peroxisomal biogenesis factor 1 |
peroxisome membrane biogenesis; cellular lipid metabolic process |
protein binding; protein homodimerization activity |
1.53 |
DHRS7C |
dehydrogenase/reductase (SDR family) member 7C |
oxidation-reduction process |
retinol dehydrogenase activity; oxidoreductase activity |
1.52 |
XRCC4 |
X-ray repair complementing defective repair in Chinese hamster cells 4 |
DNA repair, double-strand break repair |
DNA binding; protein binding; ligase activity |
1.51 |
COX8C |
cytochrome c oxidase subunit VIIIC |
mitochondrial electron transport, hydrogen ion transmembrane transport |
cytochrome-c oxidase activity |
1.51 |
PTGDS |
prostaglandin D2 synthase 21 kDa (brain) |
prostaglandin biosynthetic process, fatty acid metabolic process |
transporter activity, retinoid binding, fatty acid binding |
−1.51 |
PDLIM3 |
PDZ and LIM domain 3 |
actin filament organization |
cytoskeletal protein binding; zinc ion binding |
−1.52 |
PDK2 |
pyruvate dehydrogenase kinase, isozyme 2 |
glucose metabolic process, protein phosphorylation |
protein serine/threonine kinase activity, pyruvate dehydrogenase kinase activity |
−1.66 |
TCAP |
titin-cap |
cardiac muscle contraction, protein complex assembly |
titin binding; ion channel binding |
−1.72 |
DHRS12 |
dehydrogenase/reductase (SDR family) member 12 |
oxidation-reduction process |
oxidoreductase activity |
−1.75 |
HSD17B4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
fatty acid metabolic process, fatty acid beta-oxidation |
oxidoreductase activity |
−1.76 |
CYP4Z2P |
cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene |
oxidation-reduction process |
iron ion binding; oxidoreductase activity, heme binding |
−1.82 |
LIPK |
lipase, family member K |
lipid catabolic process; lipid metabolic process |
hydrolase activity |
−1.88 |
MT-TM |
mitochondrially encoded tRNA methionine |
tRNA Aminoacylation |
catalytic activity |