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. 2018 Jun 26;9(7):320. doi: 10.3390/genes9070320
siNFκB HCC-1954
Fold Change Gene Symbol Description GO Biological Process GO Molecular Function
1.78 HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 steroid biosynthetic process; oxidation-reduction process estradiol 17-beta-dehydrogenase activity; testosterone dehydrogenase activity
1.7 COX11P1 COX11 cytochrome c oxidase assembly homolog (yeast) pseudogene 1 mitochondrial electron transport, hydrogen ion transmembrane transport cytochrome-c oxidase activity
1.64 BRCA1 breast cancer 1, early onset DNA repair, double-strand break repair via homologous recombination DNA binding, ligase activity
1.58 FAR1 fatty acyl CoA reductase 1 glycerophospholipid biosynthetic process; oxidation-reduction process fatty-acyl-CoA reductase (alcohol-forming) activity; oxidoreductase activity
1.58 RB1 retinoblastoma 1 cell cycle checkpoint, G1/S transition of mitotic cell cycle DNA binding transcription factor activity, enzyme binding
1.57 NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 cyclic nucleotide metabolic process, inositol phosphate metabolic process hydrolase activity, endopolyphosphatase activity, protein binding
1.56 HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) fatty acid metabolic process, prostaglandin metabolic process NAD binding, prostaglandin E receptor activity, oxidoreductase activity
1.54 PEX1 peroxisomal biogenesis factor 1 peroxisome membrane biogenesis; cellular lipid metabolic process protein binding; protein homodimerization activity
1.53 DHRS7C dehydrogenase/reductase (SDR family) member 7C oxidation-reduction process retinol dehydrogenase activity; oxidoreductase activity
1.52 XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 DNA repair, double-strand break repair DNA binding; protein binding; ligase activity
1.51 COX8C cytochrome c oxidase subunit VIIIC mitochondrial electron transport, hydrogen ion transmembrane transport cytochrome-c oxidase activity
1.51 PTGDS prostaglandin D2 synthase 21 kDa (brain) prostaglandin biosynthetic process, fatty acid metabolic process transporter activity, retinoid binding, fatty acid binding
−1.51 PDLIM3 PDZ and LIM domain 3 actin filament organization cytoskeletal protein binding; zinc ion binding
−1.52 PDK2 pyruvate dehydrogenase kinase, isozyme 2 glucose metabolic process, protein phosphorylation protein serine/threonine kinase activity, pyruvate dehydrogenase kinase activity
−1.66 TCAP titin-cap cardiac muscle contraction, protein complex assembly titin binding; ion channel binding
−1.72 DHRS12 dehydrogenase/reductase (SDR family) member 12 oxidation-reduction process oxidoreductase activity
−1.75 HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 fatty acid metabolic process, fatty acid beta-oxidation oxidoreductase activity
−1.76 CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene oxidation-reduction process iron ion binding; oxidoreductase activity, heme binding
−1.82 LIPK lipase, family member K lipid catabolic process; lipid metabolic process hydrolase activity
−1.88 MT-TM mitochondrially encoded tRNA methionine tRNA Aminoacylation catalytic activity