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. 2018 Jul 20;9(7):364. doi: 10.3390/genes9070364

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Biosynthetic pathway of ansamitocin P-3 in Actinosynnema pretiosum. AP-3: ansamitocin P-3; EMP pathway: Embden Meyerhof Parnas pathway; PP pathway: pentose phosphate pathway; G3P: glyceraldehyde 3-phosphate; PEP: phosphoenolpyruvate; DHAP: dihydroxyacetone phosphate; X5P: D-xylulose 5-phosphate; UDP: uridine diphosphate; Gal: alpha-d-Galactose; E4P: erythrose 4-phosphate; S7P: sedoheptulose 7-phosphate; PRPP: 5-phosphoribosyl 1-pyrophosphate; AHBA: 3-amino-5-hydroxybenzoic acid; F6P: fructose-6-phosphate; TCA cycle: tricarboxylic acid cycle.