Table 4.
Some functional categories and related genes important for human host defense.
| ID | Gene Product Name | Log2 Fold Change |
|---|---|---|
| Positive regulation of cell migration | ||
| TCAF2 | TRPM8 channel-associated factor 2 | 2.11 |
| MMP9 | Matrix metalloproteinase-9 | 2.06 |
| LAMC2 | Laminin subunit gamma-2 | 1.97 |
| HBEGF | Proheparin-binding EGF-like growth factor | 1.84 |
| HAS2 | Hyaluronan synthase 2 | 1.46 |
| MAPK cascade involved in the innate immune response | ||
| CSF2 | Granulocyte-macrophage colony-stimulating factor | 2.86 |
| HBEGF | Proheparin-binding EGF-like growth factor | 1.84 |
| DUSP5 | Dual specificity protein phosphatase 5 | 1.57 |
| PSMB3 | Proteasome subunit beta type-3 | 1.46 |
| PPP5C | Serine/threonine-protein phosphatase 5 | 1.37 |
| PSMB2 | Proteasome subunit beta type-2 | 1.28 |
| UBB | Polyubiquitin-B | 1.24 |
| Antimicrobial humoral immune response | ||
| SERPINE1 | Plasminogen activator inhibitor 1 | 3.55 |
| SLC11A1 | Natural resistance-associated macrophage protein 1 | 2.28 |
| RNASE7 | Ribonuclease 7 | 2.27 |
| RPS19 | 40S ribosomal protein S19 | 1.66 |
| RPL30 | 60S ribosomal protein L30 | 1.41 |
| Epidermal cell differentiation | ||
| CASP14 | Caspase-14 | 3.74 |
| ALDOC | Fructose-bisphosphate aldolase C | 3.70 |
| AKR1C1 | Aldo-keto reductase family | 2.80 |
| LAMC2 | Laminin subunit gamma-2 | 1.97 |
| PGK1 | Phosphoglycerate kinase 1 | 1.62 |
| Establishment of the skin barrier | ||
| KRT1 | Keratin type II cytoskeletal 1 | −4.02 |
| FLG | Filaggrin | −1.86 |