Table 3.
Enriched Gene Ontologies terms for the 32 genes differentially expressed in synovial tissue of patients with contrast pain phenotypes.
| Gene Ontology (GO) Term | Term ID | Ontology | Gene Set Size | Differentially Expressed Genes in Set | Expected Proportion | Fold Enrichment | Direction | Adjusted p Value |
|---|---|---|---|---|---|---|---|---|
| Peripheral nervous system development | GO:0007422 | BP 1 | 74 | 4 | 0.11 | >5 | Up-regulation | 3.62 × 10−2 |
| Second-messenger-mediated signalling | GO:0019932 | BP | 149 | 5 | 0.22 | >5 | Up-regulation | 2.13 × 10−2 |
| Regulation of MAPK cascade | GO:0043408 | BP | 771 | 9 | 1.15 | >5 | Up-regulation | 9.79 × 10−3 |
| Regulation of protein phosphorylation | GO:0001932 | BP | 1330 | 11 | 1.98 | >5 | Up-regulation | 1.44 × 10−2 |
| Regulation of phosphorylation | GO:0042325 | BP | 1419 | 11 | 2.11 | >5 | Up-regulation | 2.70 × 10−2 |
| Anatomical structure morphogenesis | GO:0009653 | BP | 2341 | 14 | 3.49 | 4.02 | Up-regulation | 1.64 × 10−2 |
1 BP-biological processes.