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Comparison of ALK–EML4 fusion detection results for clinical samples.
| Method | Sample | TP Rate | TP | TN | FP | FN | Sensitivity | Specificity |
|---|---|---|---|---|---|---|---|---|
| BWA-ALN + FACTERA | 286 | 0.35% | 1 | 270 | 0 | 15 | 6.25% | 100.00% |
| BWA-ALN + CREST | 286 | 1.40% | 4 | 270 | 0 | 12 | 25.00% | 100.00% |
| BWA-MEM + FACTERA | 286 | 0.70% | 2 | 270 | 0 | 14 | 12.50% | 100.00% |
| BWA-MEM + CREST | 286 | 2.80% | 8 | 270 | 0 | 8 | 50.00% | 100.00% |
| SEGF | 286 | 3.85% | 11 | 270 | 0 | 5 | 68.75% | 100.00% |
