Table 1.
Clinical and demographic characteristics at baseline.
| Characteristic | Escitalopram (n = 105) | Duloxetine (n = 106) | F | p | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| Age (yrs) | 41.1 | 12.1 | 38.2 | 11.4 | 3.904 | 0.049 |
| Age at first episode (yrs) | 32.8 | 15.1 | 27.7 | 13.4 | 6.850 | 0.010 |
| Current episode duration (wks) | 103.8 | 159.1 | 123.9 | 237.7 | 0.514 | 0.474 |
| HDRS | 20.0 | 3.6 | 19.4 | 3.8 | 1.766 | 0.185 |
| BDI | 23.3 | 7.2 | 23.3 | 7.3 | 0.000 | 0.998 |
| HAMA | 16.6 | 5.0 | 15.1 | 5.1 | 4.335 | 0.039 |
| N | % | N | % | X 2 | P | |
| Sex | 0.379 | 0.538 | ||||
| Male | 49 | 46.7 | 45 | 42.5 | ||
| Female | 56 | 53.3 | 61 | 57.5 | ||
| Race | 1.892 | 0.864 | ||||
| White | 46 | 43.8 | 53 | 50.0 | ||
| Black | 22 | 21.0 | 20 | 18.9 | ||
| Other or Multiple | 37 | 35.2 | 33 | 31.1 | ||
| Ethnicity | 0.119 | 0.730 | ||||
| Hispanic | 33 | 31.4 | 31 | 29.2 | ||
| Non-Hispanic | 72 | 68.6 | 75 | 70.8 | ||
| Current Anxiety Disorder | 0.114 | 0.736 | ||||
| Yes | 45 | 42.9 | 43 | 40.6 | ||
| No | 60 | 57.1 | 63 | 59.4 | ||
| Previous Episodes | 2.717 | 0.257 | ||||
| 1 | 57 | 54.8 | 47 | 44.3 | ||
| 2 | 17 | 16.3 | 25 | 23.6 | ||
| ≥3 | 30 | 28.8 | 34 | 32.1 | ||
| Chronic Episode (≥2 yrs) | 29 | 28.2 | 34 | 32.4 | 0.440 | 0.507 |
Bolded values represent p < 0.05. BDI: Beck Depression Inventory; HAMA: Hamilton Anxiety Rating Scale HDRS; Hamilton Depression Rating Scale.