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. 2018 Jul 17;8(7):64. doi: 10.3390/bs8070064

Table 2.

Frequency and duration of side effects among patients treated with escitalopram or duloxetine.

Adverse Event Frequency Duration
Total Escitalopram Duloxetine p-Value Escitalopram Duloxetine p-Value
(n = 211) (n = 105) (n = 106) (n = 92) (n = 96)
n % n % n % Mean (Days) SD Mean (days) SD
Nausea 58 27.5 26 24.8 32 30.2 0.38 7.7 8.5 17.6 36.0 0.20
Headache 53 25.1 27 25.7 26 24.5 0.84 20.8 22.7 12.7 17.4 0.19
Somnolence 48 22.7 23 21.9 25 23.6 0.77 44.0 63.3 19.2 17.2 0.08
Sexual dysfunction 47 22.3 23 21.9 24 22.6 0.90 89.0 93.7 88.5 70.0 0.98
Fatigue 46 21.8 22 21 24 22.6 0.77 49.1 55.2 31.4 32.5 0.22
Insomnia 45 21.3 20 19 25 23.6 0.42 71.5 116.4 37.2 37.3 0.20
Dry mouth 41 19.4 16 15.2 25 23.6 0.13 54.4 62.9 72.3 73.4 0.43
Dizziness 33 15.6 16 15.2 17 16 0.87 38.9 78.4 10.3 11.4 0.19
Diarrhea 32 15.2 15 14.3 17 16 0.72 21.0 34.6 13.4 22.3 0.48
Constipation 20 9.5 8 7.6 12 11.3 0.36 24.6 30.0 27.2 22.6 0.83
Anxiety 18 8.5 8 7.6 10 9.4 0.64 15.8 18.3 15.4 16.9 0.97
Abdominal pain 17 8.1 6 5.7 11 10.4 0.21 12.6 15.1 9.6 9.6 0.64
Yawning 16 7.6 7 6.7 9 8.5 0.62 31.6 16.5 45.0 59.9 0.58
Appetite decreased 16 7.6 7 6.7 9 8.5 0.62 20.2 15.6 50.0 53.2 0.22
Emotional blunting 15 7.1 11 10.5 4 3.8 0.06 38.0 24.4 24.8 24.8 0.38
Dyspepsia 14 6.6 6 5.7 8 7.5 0.59 33.8 42.1 13.8 11.8 0.34
Bruxism 14 6.6 8 7.6 6 5.7 0.57 88.6 85.6 54.0 41.6 0.38
Sweating increased 13 6.2 4 3.8 9 8.5 0.16 41.3 23.4 41.3 37.1 0.99
Jitteriness 12 5.7 6 5.7 6 5.7 0.99 10.3 5.1 5.8 5.9 0.28
Restlessness 11 5.2 5 4.8 6 5.7 0.77 18.3 24.5 19.3 14.7 0.95