Table 3.
Time to onset of side effects (Days).
| Side Effect | All Patients | Escitalopram | Duloxetine | p-Value | |||
|---|---|---|---|---|---|---|---|
| (n = 793) | (n = 372) | (n = 421) | |||||
| Mean | SD | Mean | SD | Mean | SD | ||
| Dry mouth | 5.1 | 7.8 | 5.0 | 6.4 | 5.2 | 8.6 | 0.93 |
| Dyspepsia | 6.6 | 10.6 | 5.0 | 7.8 | 7.9 | 12.8 | 0.64 |
| Appetite decreased | 6.7 | 14.2 | 5.7 | 9.7 | 7.3 | 17.2 | 0.83 |
| Jitteriness | 8.6 | 13.3 | 12.0 | 15.9 | 5.1 | 10.1 | 0.36 |
| Yawning | 9.8 | 13.7 | 10.6 | 13.5 | 9.1 | 14.5 | 0.82 |
| Nausea | 10.1 | 17.6 | 10.1 | 14.7 | 10.1 | 20.0 | 0.99 |
| Restlessness | 10.8 | 14.3 | 10.8 | 14.6 | 10.7 | 15.4 | 0.99 |
| Diarrhea | 12.1 | 18.3 | 13.3 | 15.4 | 11.2 | 20.7 | 0.75 |
| Fatigue | 12.6 | 18.2 | 13.2 | 17.6 | 12.1 | 19.1 | 0.83 |
| Anxiety | 12.6 | 19.3 | 16.4 | 21.3 | 9.2 | 17.7 | 0.43 |
| Abdominal pain | 13.3 | 12.8 | 13.5 | 13.3 | 13.2 | 13.1 | 0.96 |
| Headache | 13.8 | 18.2 | 15.2 | 18.0 | 12.1 | 18.5 | 0.49 |
| Constipation | 14.3 | 14.7 | 17.3 | 17.7 | 12.3 | 12.6 | 0.43 |
| Insomnia | 14.8 | 16.8 | 15.3 | 16.3 | 14.4 | 17.6 | 0.86 |
| Dizziness | 15.6 | 19.5 | 12.6 | 15.2 | 18.6 | 23.1 | 0.35 |
| Somnolence | 15.6 | 19.2 | 19.2 | 20.4 | 12.2 | 17.7 | 0.19 |
| Sweating increased | 19.0 | 15.9 | 13.3 | 12.3 | 21.6 | 17.3 | 0.41 |
| Bruxism | 19.9 | 19.8 | 20.2 | 19.7 | 19.6 | 21.5 | 0.95 |
| Sexual dysfunction | 20.9 | 21.1 | 25.5 | 21.5 | 16.7 | 20.1 | 0.11 |
| Emotional blunting | 23.5 | 18.0 | 20.9 | 15.2 | 30.5 | 25.6 | 0.38 |