Skip to main content
. 2018 Mar 19;32(8):4544–4559. doi: 10.1096/fj.201701374R

Figure 2.

Figure 2

GlatmTg(CAG-A4GALT) mice exhibit a water- and salt-loss phenotype. A) Water intake, urine volume, and urine osmolality (Uosm). B) Daily urinary excretion of solutes. C) FE of solutes. D) Blood chemistry. Total protein (TP), albumin (Alb), blood urea nitrogen (BUN), Cr, Na, K, Cl, Ca, Mg, and plasma osmolality (Posm). GlatmTg(CAG-A4GALT): 5 (n = 8), 10 (n = 7), and 20 wk old (n = 7); WT mice: 5 (n = 8), 10 (n = 10), and 20 wk old (n = 10). E) Systolic (S) BP and diastolic (D) BP. GlatmTg(CAG-A4GALT) mice: 5 (n = 19), 10 (n = 16), and 20 wk old (n = 12); WT mice: 5 (n = 20), 10 (n = 17), and 20 wk old (n = 14). In box-and-whisker plots, center lines represent the median, limits represent quartiles, whiskers represent the 10th and 90th percentiles, black diamonds represent minima or maxima outside the reach of whiskers, and red lines represent the mean. Differences between groups were evaluated by using Student’s t test; data are shown as t (integral degree of freedom) = t, P. For Welch’s t test, data are shown as t (mixed decimal degree of freedom) = t, P. For the Wilcoxon rank-sum test, data are shown with a P value only.