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. 2018 Jul 27;12:1179554918790563. doi: 10.1177/1179554918790563

Table 2.

The 5-year disease-free survival estimated by univariate Cox analysis for 447 women diagnosed with breast cancer (Juiz de Fora, Brazil, 2003-2005).

Variable TNBC
Non-TNBC
HR 95% CI P value HR 95% CI P value
Age at diagnosis, y
 <40 vs ⩾40 1.15 0.28–4.77 .85 1.91 1.10-3.34 .02
Ethnicity
 Nonwhite vs white 1.47 0.76–2.88 .26 1.91 1.16–3.16 .01
Education level
 Low/moderate vs high 1.55 0.67–3.58 .3 1.92 1.19–3.10 .01
Health services
 Public vs private 1.16 0.60–2.24 .66 1.4 0.92–2.12 .12
Chemotherapy
 Yes vs no 0.9 0.38–2.17 .82 1.74 1.08–2.82 .02
Tumor size, cm
 >2 vs ⩽2 1.4 0.67–2.90 .37 2.58 1.59–4.19 <.001
Lymph node involvement
 Positive vs negative 2.15 1.07–4.31 .03 2.28 1.47–3.53 <.001
Tumor grade
 III vs I-II 0.88 0.42–1.82 .73 2.23 1.28–3.89 .01
Staging
 III vs I-II 1.89 0.98–3.64 .05 3.89 2.56–5.90 <.001
p53
 Moderate/high vs low 1.07 0.53–2.16 .86 1.88 1.16–3.05 .01
Ki67
 Moderate/high vs low 0.91 0.39–2.11 .83 2.06 1.08–3.94 .03
Multifocality
 Yes vs no 1.53 0.63–3.68 .34 1.62 0.81–3.22 .17
Multicentricity
 Yes vs no 2.46 0.87–7.01 .09 1.7 0.74–3.90 .21
Lymphocytic infiltration
 Positive vs negative 1.47 0.74–2.92 .27 1 0.65–1.54 .99

Abbreviations: CI, confidence interval; HR, hazard ratio; TNBC, triple-negative breast cancer.